Administration of antineoplastic drugs and fecundity in female nurses

Regional Administration of Antineoplastic Drugs

Regional antineoplastic drug delivery is not a new concept. Following the initial recognition that cytotoxic alkylating agents could cause shrinkage of tumor masses and a reduction in the quantity of malignant ascites in patients with advanced ovarian cancer, investigators in the 1950s instilled the drugs directly into the peritoneal cavity in an effort to treat the malignancy (1). Similarly, i...

hematological changes in nurses handling antineoplastic drugs

a cross-sectional study to determine whether occupational exposure to antineoplastic drugs can cause hematologic changes was performed. blood samples were collected from a group of 24 hematology/oncology nurses who were exposed to antineoplastic drugs during a mean preiod of 5.5 years (standard error =1.1). the control group, matched by sex, and age, consisted of 18 nurses, worked on other sect...

The Occupational Hazards of Exposure to Antineoplastic and Chemotherapy Drugs in Nurses. A systematic review

Background: By increasing the incidence of cancer, the use of antineoplastic drugs and consequently, oncology nurses’ exposure to the drugs during daily activities has increased. Because of the importance of professional Nurses' health, the purpose of this study is to answer the question of what risks contact with antineoplastic and chemotherapy drugs in nurses?        Method: Studies on the h...

2 Regional Administration of Antineoplastic Drugs

Regional antineoplastic drug delivery is not a new concept. Following the initial recognition that cytotoxic alkylating agents could cause shrinkage of tumor masses and a reduction in the quantity of malignant ascites in patients with advanced ovarian cancer, investigators in the 1950s instilled the drugs directly into the peritoneal cavity in an effort to treat the malignancy (1). Similarly, i...

The Potential Genotoxic Effects of Antineoplastic Drugs in Occupationally Exposed Nurses